An introduction to genetic epidemiology
- Author/Editor(s):
- Lyle J. Palmer, Paul R. Burton, George Davey Smith
- Format:
- Hardback, 256 pages, 240 x 172 mm
- ISBN
- 9781861348982
- Published:
- 31 May 2011
- Series:
- Health and Society series
£48.00 - List price: £60.00 You save: £12.00
North America customers can order this book here from the University of Chicago Press.
"This book should be incredibly useful to students and researchers at all levels in genetic epidemiology. For students it offers an eminently readable and accessible foundation, and for researchers, a superb source to fill in missing pieces in our knowledge."
Ezra Susser, Professor of Epidemiology and Psychiatry, Mailman School of Public Health, Columbia University, and New York State Psychiatric Institute
"This is a sobering must-read for anyone who wishes to know how genetic epidemiology may change how we understand, treat or prevent human disease."
Robert Elston, Case Western Reserve University School of Medicine
About This Book
Genetic epidemiology is a very rapidly developing field that has acquired a central role in modern biomedical science. Until now there has been no comprehensive introductory text for students and academics who do not have specialised training in statistics or genetics. This book begins with a primer in human molecular genetics and then examines standard methods in population genetics and genetic epidemiology required for an adequate grounding in the field. Among much else, the book contains discussion of the public health aspects of the new genetics, and of epidemiological methods for studying genes and environmental factors in complex diseases. Written by leading international experts and supplemented by a glossary and in-chapter guides to further reading, this essential textbook will be widely welcomed by teachers and students on many courses internationally.
Author Biography
Lyle J. Palmer is Professor of Biostatistics and Epidemiology at the University of Toronto, Canada. Paul R Burton is Professor of Genetic Epidemiology at the University of Leicester, UK. George Davey Smith is Professor of Clinical Epidemiology at the University of Bristol, UK.Contents
Key concepts in genetic epidemiology ~ Paul R Burton, Martin D Tobin and John L Hopper
Genetic linkage studies ~ M Dawn Teare and Jennifer H. Barrett
Genetic association studies ~ Heather J. Cordell and David G. Clayton
Mapping complex disease genes using linkage disequilibrium and genome-wide association scans ~ Lyle J Palmer, Nicholas J Timpson, David M Evans, George Davey Smith and Lon R Cardon
A question of standards: what makes a good genetic association study? ~ Andrew T Hattersley and Mark I McCarthy
Biobanks and biobank harmonisation ~ Paul R Burton, Isabel Fortier, Mylene Deschênes, Anna Hansell and Lyle J Palmer
Population health aspects of genetic epidemiology: genomic profiling, personalised medicine, and Mendelian randomisation ~ George Davey Smith, Shah Ebrahim, Sarah Lewis and Lyle J Palmer.
Customers in Australia, New Zealand, Papua New Guinea, Taiwan, Malaysia and Brunei must order from their local distributor